Reclast patient assistance program reclast patient assistance program novartis. Reclast contains the same active ingredient found in zometa. Please see indications and important safety information on page 2, and the accompanying prolia full prescribing information, including medication guide. A patient that is already receiving zometa should not be treated with reclast. Zoledronic acid is a powerful type of bisphosphonate. Side effects are listed in the following table in the order in which they may occur.
Zoledronic acid clearance was independent of dose but dependent upon the patients creatinine clearance. Reclast is the brand name of the prescription drug zoledronic acid, used to treat and prevent osteoporosis a condition in which bones become weak and may break easily it may also be used to. Medication guide zoledronic acid injection what is the. Zoledronic acid aclasta for osteoporosis nps medicinewise. Reclast is contraindicated in patients with creatinine clearance less than 35 mlmin and in those with evidence of acute renal impairment see contraindications 4. Physicians and other health care professionals are encouraged to consult other sources and confirm the information. Drink two 2 glasses of fluids, such as water, within a few hours. If zoledronic acid is chosen, there are sufficient data in men with crpc to support dosing of zoledronic acid every 12 weeks medicationrelated osteonecrosis of the jaw in patients with. Its high affinity to and long halflife in bone, and long duration of action, allow for onceyearly administration, which has. Patient has been instructed to drink at least 2 glasses of fluids within a few hours prior to infusion zoledronic acid reclast 5 mg in 100 mlto be infused over 30 minutes in the special procedures unit of the outpatient center provide patient information sheet to patient. In postmenopausal women with osteoporosis, diagnosed by bone mineral density bmd or prevalent vertebral fracture, reclast reduces the incidence of fractures hip, vertebral and nonvertebral osteoporosisrelated fractures. Information for the user zoledronic acid accord 4 mg5 ml concentrate for solution for infusion zoledronic acid read all of this leaflet carefully before you are given this medicine because it contains important information. It is also approved to increase bone mass in men with osteoporosis and for the prevention of new clinical fractures in patients who have recently had a lowtrauma hip fracture. May 08, 2020 reclast and zometa are two different brands of zoledronic acid.
This medication guide summarizes the most important information about reclast. Reclast and zometa contain the same active ingredient. Ibandronate boniva and zoledronic acid reclast, zometa are bisphosphonates. Reclast reclast zoledronic acid injection read the medication guide that comes with reclast before you start taking it and each time you get a refill.
There have been reports of bronchoconstriction in aspirinsensitive patients receiving bisphosphonates, including reclast. Your low blood calcium must be treated before you take reclast. Zoledronic acid clearance was independent of dose but dependent upon the patient s creatinine clearance. Patients receiving zometa should not receive reclast 5. Intravene reclast zoledronic acid infusion orders rev 102018 please fax this form along with a copy of insurance cards and clinical documentation to 4344555531 or call 14349473900 ext. This patients benefit plan requires prior authorization for certain medications in order for the drug to be covered. None zoledronic acid does not inhibit any cyp450 enzymes in vitro. These include osteoporosis, high blood calcium due to cancer, bone breakdown due. Zoledronic acid has been shown to prevent the bone loss seen in 62 adult patients who had received a liver transplant for chronic liver disease. You may eat normally before receiving your infusion. Im looking for information on prolia and reclast as alternatives to boniva. Each of the side effects above was reported in 10% or greater of patients treated with zoledronic acid. Unlike other common bisphosphonates that are taken by. Novartis reclast patient information sheet keyword after analyzing the system lists the list of keywords related and the list of websites with related content, in addition you can see which.
Zoledronic acid zometa, reclast prior auth criteria proprietary information. Patients must receive adequate hydration prior to the administration of reclast. The related drug information index provides comprehensive access to all drug information related to a specific drug types of content include full prescribing information, drug summaries, full prescribing information continuing medication education full pi cme, medication guides, risk evaluation and mitigation strategies rems summaries, rems continuing medication education rems cme, and. This fax may contain medical information that is privileged and. May 08, 2020 these are not all the possible side effects of reclast. Cvs caremark administers the prescription benefit plan for the patient identified. The rate of any new clinical fracture minus digital or facial fractures or fractures in abnormal bone was reduced significantly in patients receiving zoledronic acid 8. Zoledronic acid reclast zoledronic acid is a bisphosphonate prescribed to prevent or treat osteoporosis or pagets disease. Zoledronic acid monohydrate is a white crystalline powder. Dec 23, 2019 reclast zoledronic acid sometimes called zoledronate is a bisphosphonate medicine that alters bone formation and breakdown in the body. Please also read the package leaflet of zoledronic acid 5 mg for more information. If you would like more information, talk with your doctor.
All of the drugs you mention are used to treat postmenopausal women with osteoporosis, although theyre in different drug classes. Most people with low blood calcium levels do not have symptoms, but some people may have symptoms. Effect of intravenous zoledronic acid on tibiofemoral. If you have any further questions, ask your doctor or pharmacist. Reclast zoledronic acid sometimes called zoledronate is a bisphosphonate medicine that alters bone formation and breakdown in the body. The clinical information contained in the via pathways and via portal are intended as a supplement to, and not a substitute for, the knowledge, expertise, skill, and judgment of physicians, pharmacists and other healthcare professionals involved with patient care at client facilities. You can ask your doctor or pharmacist for information. It is also used in the treatment of multiple myeloma andor bone. Zoledronic acid is used to treat high levels of calcium in the blood hypercalcemia. Zoledronic acid reclast order form infusion solutions, inc. If you have low blood calcium before you start taking reclast, it may get worse during treatment. Description zoledronic acid reclast, zometa is a bisphosphonate. Reclast zoledronic acid dose, indications, adverse effects. Zoledronic acid zoledronic acid this product information is intended only for residents of the united states.
Zoledronic acid reclast is a biologic reference guide with prescribing information, dosage. Medications administered by a healthcare professional most insurance companies cover medications administered by a healthcare professional in a medical office or hospital such as a drug that is given by intravenous infusion. Affected cytochrome p450 isoenzymes and drug transporters. Importance a proofofprinciple study suggested that intravenous zoledronic acid may reduce knee pain and the size of bone marrow lesions in people with knee osteoarthritis, but data from large trials are lacking objective to determine the effects of intravenous zoledronic acid on knee cartilage volume loss in patients. Zoledronic acid reclast zoledronic acid is approved for the prevention and treatment of osteoporosis in postmenopausal women. It is also approved to increase bone mass in men with osteoporosis and for the prevention of new clinical fractures in patients.
A single dose of reclast should not exceed 5 mg and the. All information contained within the johns hopkins arthritis center website is intended for educational purposes only. Restricted access do not disseminate or copy without approval. The related drug information index provides comprehensive access to all drug information related to a specific drug types of content include full prescribing information, drug summaries, full prescribing information. Sep 01, 2019 reclast should not be given if the patient is pregnant or plans to become pregnant, or if she is breastfeeding see warnings and precautions 5. For more information, ask your doctor or pharmacist.
Insurance verification and prior authorization form. Reclast contains zoledronic acid, a bisphosphonic acid which is an inhibitor of osteoclastic bone resorption. Read the medication guide and, if available, the patient information leaflet provided by your pharmacist before you start using this product and each. In a study in patients with cancer and bone metastases, increasing the infusion time of a 4 mg dose of zoledronic acid from 5 minutes n5 to 15 minutes n7 resulted in a. Reclast is used to treat or prevent osteoporosis caused by menopause, steroid use, or gonadal failure. Information for the user prolia 60 mg solution for injection in prefilled syringe denosumab read all of this leaflet carefully before you start using this medicine because it contains important information for you. Uptodate, electronic clinical resource tool for physicians and patients that provides information on adult primary care and internal medicine, allergy and immunology, cardiovascular medicine, emergency medicine, endocrinology and diabetes, family medicine, gastroenterology and hepatology, hematology, infectious diseases, nephrology and. Zoledronic acid reclast national osteoporosis foundation. Zoledronic acid was initiated within 90 days of surgical repair. Read the medication guide and, if available, the patient information leaflet provided by your pharmacist before you start using this product and each time you. Reclast zoledronic acid injection side effects, images. Reclast is also used to treat pagets disease of bone.
Reclast and zometa are two different brands of zoledronic acid. See 17 for patient counseling information and medication. Dailymed zoledronic acid zoledronic acid injection. What you need to know about paying for your osteoporosis medications. Contact information 1800 8330166 phone physician requests should be directed to. Zoledronic acid is structurally similar to pamidronate. Patient information once weekly fosamax fossahmax alendronate sodium tablets and oral solution read this information before you start taking fosamax. Reclast is indicated for treatment of osteoporosis in postmenopausal women.
By completing and faxing this form, you represent that your patient is aware of the disclosure of their personal health information to amgen and its agents for. Reclast patient information handout keyword found websites. Also, read the leaflet each time you refill your prescription, just in case anything has changed. Zoledronic acid intravenous route description and brand. Alendronate fosamax, risedronate actonel, and ibandronate boniva. Reclast is used to treat osteoporosis caused by menopause, steroid use, or gonadal failure. Zoledronic acid is approved for the prevention and treatment of osteoporosis in postmenopausal women. Novartis reclast patient information sheet keyword found. Zoledronic acid reclast zoledronic acid is a bisphosphonate. You should not receive reclast if you are already receiving zometa. Unlike other common bisphosphonates that are taken by mouth, reclast bypasses the stomach because it is an infusion into the bloodstream. Zoledronic acid should not be prescribed if the patient is receiving zometa. This leaflet does not take the place of discussions with your doctor. If you have questions or doubts, talk to your doctor, nurse or pharmacist.
Zoledronic acid is indicated for the prevention of skeletalrelated events sres such as pathological fractures, bone pain, spinal compression, need for bone radiation, or surgery in patients. Reclast fda prescribing information, side effects and uses. See important reminder at the end of this policy for important regulatory and legal information. See 17 for patient counseling information and medication guide. Patient has received randolph health reclast information sheet 9.
Call your doctor for medical advice about side effects. See what others have said about reclast, including the effectiveness, ease of use and side effects. Drink two 2 glasses of fluids, such as water, within a few hours before receiving reclast to help prevent kidney problems 3. Its molecular formula is c 5 h 10 n 2 o 7 p 2 h 2 o and a molar mass of 290. Reclast zoledronic acid dose, indications, adverse.
This medication guide does not take the place of talking with your doctor about your medical condition or treatment. Zoledronic acid can protect and strengthen bones in people with myeloma or some types of cancer that have spread to the bone. In postmenopausal women with osteoporosis, diagnosed by bone mineral density bmd or prevalent vertebral fracture, reclast reduces the incidence of fractures hip. You can ask your doctor or pharmacist for information about reclast that is written for health professionals. Physicians and other health care professionals are encouraged to consult other sources and confirm the information contained within this site. This medicine is for use when you have a high risk of bone fracture due to osteoporosis. Reclast may lower the calcium levels in your blood. Nov 18, 2016 zoledronic acid reclast, aclasta is an intravenous, highly potent aminobisphosphonate approved worldwide, including in the usa, eu and japan for use in patients with primary or secondary osteoporosis or low bone mass approved indications vary between countries. Novartis reclast patient information sheet keyword after analyzing the system lists the list of keywords related and the list of websites with related content, in addition you can see which keywords most interested customers on the this website. Medication guide zoledronic acid injection what is the most. Highlights of prescribing information these highlights do not include all the information needed to use reclastsafely and effectively. Zoledronic acid, also known as zoledronate, is a medication used to treat a number of bone diseases. Highlights of prescribing information tymlos safely and. Highlights of prescribing information may worsen during.
In preclinical models, zoledronic acid prevents tumour adhesion to the bone, induces tumour cell apoptosis, and inhibits angiogenesis. Rarely patients have reported severe bone, joint and muscle pain that begins from 1 day to one month after starting any bisphosphonate, including zolendronic. Bone is a living tissue constantly being remodeled. What is the most important information i should know about reclast. This can slow bone loss and may help prevent bone fractures. Zoledronic acid injection is used to treat hypercalcemia high levels of calcium in the blood that may occur in patients with some types of cancer.
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